Abstract

INTRODUCTION AND OBJECTIVES:The American Urologic Association Guidelines recommends obtaining a 24-hour urine (24HU) in recurrent stone formers, patients high-risk for stone recurrence, and interested first-time stone formers. However, the advantage of selective therapy based on 24HU results over empiric treatment is unclear. We aimed to determine if obtaining a 24HU in high risk stone formers is associated with decreased recurrent stone episodes in a contemporary cohort exemplifying real-world clinical practice.METHODS:We used the MarketScan database to identify insured, employed subjects, 18 to 64 years old with a primary diagnosis of kidney and/or ureteral stones based on ICD-9 and ICD-10 diagnosis codes from 2008 to 2014. Subjects at high risk for infectious stones or with cystinuria were excluded. High risk stone formers (based on AUA guidelines), those undergoing stone surgery, and those with previous stone diagnoses one year prior to the date of inclusion were characterized with CPT and ICD codes, ...

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