MP06-18 CT VOLUMETRY OF THE KIDNEY IS A COST EFFECTIVE ALTERNATIVE TO MAG3 SCAN IN PREDICTING RENAL FUNCTION AFTER DONOR NEPHRECTOMY

Abstract

You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation & Vascular Surgery I1 Apr 2017MP06-18 CT VOLUMETRY OF THE KIDNEY IS A COST EFFECTIVE ALTERNATIVE TO MAG3 SCAN IN PREDICTING RENAL FUNCTION AFTER DONOR NEPHRECTOMY Yosuke Mitsui, Takuya Sadahira, Motoo Araki, Shingo Nishimura, Koichiro Wada, Yasuyuki Kobayashi, Toyohiko Watanabe, and Yasutomo Nasu Yosuke MitsuiYosuke Mitsui More articles by this author , Takuya SadahiraTakuya Sadahira More articles by this author , Motoo ArakiMotoo Araki More articles by this author , Shingo NishimuraShingo Nishimura More articles by this author , Koichiro WadaKoichiro Wada More articles by this author , Yasuyuki KobayashiYasuyuki Kobayashi More articles by this author , Toyohiko WatanabeToyohiko Watanabe More articles by this author , and Yasutomo NasuYasutomo Nasu More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.263AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES In selecting living kidney donor, we need to evaluate split renal function. We routinely use Tc-99m-mercapto-acetyltriglycin (MAG3). However, all transplant programs do not use MAG3 because of its high cost and radiation exposure. Computed tomography (CT) volumetry of the kidney is a new tool to evaluate split renal function. Since CT scan is used in all transplant programs for preoperative evaluation, CT volumetry adds no cost. If we can substitute CT volumetry for MAG3, donor can avoid extra radiation exposure and save some money. We examined the correlation between MAG3 and CT volume of the kidney. Moreover, we evaluate which is a better method to predict post-operative donor′s renal function (1, 3, 12 months). METHODS Sixty-three patients underwent donor nephrectomy from 2009 to 2016 in our institution. Those who did not perform thin slice CT (1mm), and those with follow up less than 1 year were excluded. Thirty-four living kidney donors were included in this retrospective study. Renal volume was automatically calculated by volume analyzer software (SYNAPSE VINCENT, FUJIFILM, Tokyo, Japan). The correlation was evaluated using Bland-Altman plot. RESULTS Median age is 60.5 years, and the rate of male is 50%. All patients underwent left side donor nephrectomy. Preserved parenchymal volume is 139.6ml, and preserved cortex volume is 102.0ml. eGFR decreased by 36.8% from 72.0 mL/min/1.73m2 at baseline to 47.8 mL/min/1.73m2 at 1 year post-donation. A strong correlation was observed in split function measured by between MAG3 and cortex volume (R=0.92) (Fig. 2) preoperatively. Moreover, post-op eGFR was correlated with split function measured by between MAG3 and cortex volume (Fig 3). There are no significant differences in correlation between MAG3 and CT volumetry of the kidney at the each follow-up period (1, 3, 12 months) (Fig. 3). CONCLUSIONS CT volumetry is an alternative to MAG3 to evaluate split renal function and to predict postoperative renal function. It is cost effective and beneficial by reducing extra radiation exposure to a donor. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e80 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Yosuke Mitsui More articles by this author Takuya Sadahira More articles by this author Motoo Araki More articles by this author Shingo Nishimura More articles by this author Koichiro Wada More articles by this author Yasuyuki Kobayashi More articles by this author Toyohiko Watanabe More articles by this author Yasutomo Nasu More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...