Abstract

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I1 Apr 2018MP05-15 THE EORTC QLQ-C30 QUESTIONNAIRES PREDICTS EARLY AND LONG-TERM INCONTINENCE IN PATIENTS TREATED WITH ROBOTIC RADICAL PROSTATECTOMY: ANALYSIS OF A LARGE SINGLE CENTER COHORT Cosimo De Nunzio, Antonio Luigi Pastore, Riccardo Lombardo, Fabiana Cancrini, Antonio Carbone, Andrea Fuschi, Lorenzo Dutti, John H. Witt, and Andrea Tubaro Cosimo De NunzioCosimo De Nunzio More articles by this author , Antonio Luigi PastoreAntonio Luigi Pastore More articles by this author , Riccardo LombardoRiccardo Lombardo More articles by this author , Fabiana CancriniFabiana Cancrini More articles by this author , Antonio CarboneAntonio Carbone More articles by this author , Andrea FuschiAndrea Fuschi More articles by this author , Lorenzo DuttiLorenzo Dutti More articles by this author , John H. WittJohn H. Witt More articles by this author , and Andrea TubaroAndrea Tubaro More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.186AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Several risk factors including age, sexual function, surgical technique, patients’ characteristics including health status and quality of life have been associated with post radical retropubic prostatectomy incontinence. The aim of our study was to evaluate possible risk factors of post radical prostatectomy urinary incontinence. METHODS Between 2012 and 2017, all patients undergoing robotic radical prostatectomy (RRP) for prostate cancer were enrolled. Demographic, clinical and histological characteristics of the patients were recorded. Erectile dysfunction, urinary incontinence and quality of life were evaluated at baseline and at 3, 6 and 12 months postoperatively. Incontinence was evaluated with the ICIQ questionnaire, erectile dysfunction with the IIEF questionnaire and quality of life with the EORTC QLQ-C30. Incontinence was defined as ICIQ-UI short form question 3 (Q3) =4. Moderate/severe incontinence was defined as ICIQ-UI short form question 4 (Q4) =4. Multivariate logistic regression analysis were used to evaluate the risk of postoperative incontinence and of moderate/severe incontinence. RESULTS Overall 4603 patients were enrolled. Median age was 65 (IQR: 60/70) years, median BMI was 26.6 (IQR:25/29) kg/m2, median PSA was 7.4 (IQR:5.5/11) ng/ml and median prostate volume was 39 (IQR:30/52) ml. Incontinence rates at 3, 6 and 12 months were respectively 17%, 3% and 3%. On multivariate analysis, age, nerve sparing procedure, lower urinary tract symptoms and preoperative quality of life were predictors of early incontinence and incontinence severity. As well age, nerve sparing procedure, lower urinary tract symptoms and preoperative quality of life were predictors of late incontinence. CONCLUSIONS In our study a comprehensive evaluation of pre-operative patients’ quality of life, assessed by the EORTC QLQ-C30 questionnaire, can predict the risk early moderate/severe incontinence (evaluated using standardized questionnaire) in patients treated with robotic radical prostatectomy. Further studies should confirm our results. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e48-e49 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Cosimo De Nunzio More articles by this author Antonio Luigi Pastore More articles by this author Riccardo Lombardo More articles by this author Fabiana Cancrini More articles by this author Antonio Carbone More articles by this author Andrea Fuschi More articles by this author Lorenzo Dutti More articles by this author John H. Witt More articles by this author Andrea Tubaro More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...

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