MP05-20 HISTOPATHOLOGIC CORRELATION OF PIRADS VERSION 2 LESIONS ON 3T MULTIPARAMETRIC PROSTATE MRI

Abstract

You have accessJournal of UrologyImaging/Radiology: Uroradiology I1 Apr 2016MP05-20 HISTOPATHOLOGIC CORRELATION OF PIRADS VERSION 2 LESIONS ON 3T MULTIPARAMETRIC PROSTATE MRI Corinne C. Liu, Kaitlin E. Kosinski, Jeffrey T. Schiff, and Aaron E. Katz Corinne C. LiuCorinne C. Liu More articles by this author , Kaitlin E. KosinskiKaitlin E. Kosinski More articles by this author , Jeffrey T. SchiffJeffrey T. Schiff More articles by this author , and Aaron E. KatzAaron E. Katz More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1997AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Prostate Imaging Reporting and Data System (PIRADS) Version 2 was recently issued by The American College of Radiology. Each score, from 1 to 5, corresponds to the likelihood of clinically significant cancer. We aim to evaluate the correlation between a higher PIRADS score and the presence of high grade tumor on histopathology. METHODS 300 consecutive 3T Multiparametric Prostate MRI (MP-MRI) were identified from March 26, 2012 to June 29, 2015. We reviewed patient charts and a total of 102 patients underwent either a transrectal ultrasound guided (TRUS) biopsy or a total prostatectomy after the MP-MRI. 34 patients were excluded due to prior radiation or cryoablation to the prostate, leaving 68 treatment naive patients (44 - 84 years). MP-MRIs were re-interpreted utilizing the new PIRADS V.2 scoring system and correlated with pathology findings. Statistical comparisons were made using R (v.3.1.2) and Fisher’s exact test. RESULTS High grade (Gleason 8-10) tumors were found only in MP-MRI with a PIRADS score of 5 and a higher percentage of tumor is found in MP-MRI with PIRADS scores of 4 and 5 (80%) when compared to PIRADS scores of 2 and 3 (32%). Low grade (Gleason 6-7) tumors were also found in both PIRADS 4 and 5 categories. There was a significant relationship between a higher PIRADS score and a finding of cancer on pathology (p = 0.0003, OR=0.118, 95% CI 0.03-0.41). CONCLUSIONS The PIRADS scoring system is a useful tool in suggesting the likelihood of clinically significant cancer, with high grade tumors found only in MP-MRI with a score of PIRADS 5. However, MP-MRI and PIRADS criteria alone are not sufficient for determining clinically significant prostate cancer since both high grade and low grade tumors were found in PIRADS 5 and 4 categories. Correlation with other clinical parameters and biopsy is required for confirmation. A larger scale study would be helpful for further delineation. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e44-e45 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Corinne C. Liu More articles by this author Kaitlin E. Kosinski More articles by this author Jeffrey T. Schiff More articles by this author Aaron E. Katz More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...