MP03-10 LIFE EXPECTANCY IN METASTATIC UROTHELIAL BLADDER CANCER PATIENTS ACCORDING TO RACE/ETHNICITY

Abstract

You have accessJournal of UrologyCME1 May 2022MP03-10 LIFE EXPECTANCY IN METASTATIC UROTHELIAL BLADDER CANCER PATIENTS ACCORDING TO RACE/ETHNICITY Francesco Chierigo, Christoph Würnschimmel, Rocco Simone Flammia, Benedikt Horlemann, Gabriele Sorce, Benedikt Hoeh, Zhe Tian, Fred Saad, Markus Graefen, Michele Gallucci, Alberto Briganti, Francesco Montorsi, Felix K.H. Chun, Shahrokh F. Shariat, Guglielmo Mantica, Maro Borghesi, Nazareno Suardi, Carlo Terrone, and Pierre I. Karakiewicz Francesco ChierigoFrancesco Chierigo More articles by this author , Christoph WürnschimmelChristoph Würnschimmel More articles by this author , Rocco Simone FlammiaRocco Simone Flammia More articles by this author , Benedikt HorlemannBenedikt Horlemann More articles by this author , Gabriele SorceGabriele Sorce More articles by this author , Benedikt HoehBenedikt Hoeh More articles by this author , Zhe TianZhe Tian More articles by this author , Fred SaadFred Saad More articles by this author , Markus GraefenMarkus Graefen More articles by this author , Michele GallucciMichele Gallucci More articles by this author , Alberto BrigantiAlberto Briganti More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , Felix K.H. ChunFelix K.H. Chun More articles by this author , Shahrokh F. ShariatShahrokh F. Shariat More articles by this author , Guglielmo ManticaGuglielmo Mantica More articles by this author , Maro BorghesiMaro Borghesi More articles by this author , Nazareno SuardiNazareno Suardi More articles by this author , Carlo TerroneCarlo Terrone More articles by this author , and Pierre I. KarakiewiczPierre I. Karakiewicz More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002515.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To compare observed overall survival vs age-adjusted life-table (LT) derived life expectancy (LE) in metastatic urothelial bladder cancer (MBCa) patients according to race/ethnicity. METHODS: We identified Caucasian, African American, Hipanic/Latino and Asian metastatic urothelial bladder cancer patients from 2004 to 2011 within the Surveillance, Epidemiology and End Results database to. Social Security Administration tables were used to compute five-year LE. LT-derived LE was compared with observed overall survival OS. Additionally, we relied on Poisson regression plots to display cancer-specific mortality (CSM) relative to other-cause mortality (OCM) for each race/ethnicity. RESULTS: Overall, 2,286 MBCa patients were identified. Of those, 1,800 (79%) were Caucasian vs 212 (9.3%) African American vs 189 (8.3%) Hispanic/Latino vs 85 (3.7%) Asians. The median age at diagnosis was 71 years for Asians vs 70 for Caucasians vs 67 for Hispanic/Latinos vs 67 for African Americans. African Americans showed the biggest difference between observed OS and LT-predicted LE at five years (-83.8%), followed by Hispanic/Latinos (-81%), Caucasians (-77%) and Asian patients (-69%). In Poisson regression plots, Hispanic/Latinos displayed the highest cancer-specific mortality rate (88%), while African/Americans showed the highest other cause mortality rate (12%). Conversely, Asian patients displayed the lowest CSM rate (83%) and second-lowest OCM rate (7%). CONCLUSIONS: African Americans showed the least favorable survival profile in MBCa, despite being youngest at diagnosis. Contrarily, Asians displayed the best survival profile in MBCa, despite being oldest at diagnosis. Source of Funding: no funding © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e23 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Francesco Chierigo More articles by this author Christoph Würnschimmel More articles by this author Rocco Simone Flammia More articles by this author Benedikt Horlemann More articles by this author Gabriele Sorce More articles by this author Benedikt Hoeh More articles by this author Zhe Tian More articles by this author Fred Saad More articles by this author Markus Graefen More articles by this author Michele Gallucci More articles by this author Alberto Briganti More articles by this author Francesco Montorsi More articles by this author Felix K.H. Chun More articles by this author Shahrokh F. Shariat More articles by this author Guglielmo Mantica More articles by this author Maro Borghesi More articles by this author Nazareno Suardi More articles by this author Carlo Terrone More articles by this author Pierre I. Karakiewicz More articles by this author Expand All Advertisement PDF DownloadLoading ...