MP03-16 RENAL CANCER WITH VENOUS THROMBUS - HOW DIFFERENT RENAL VEIN AND INFERIOR VENA CAVA INVOLVEMENT REALLY ARE?

Abstract

You have accessJournal of UrologyKidney Cancer: Advanced (including Drug Therapy) I1 Apr 2016MP03-16 RENAL CANCER WITH VENOUS THROMBUS - HOW DIFFERENT RENAL VEIN AND INFERIOR VENA CAVA INVOLVEMENT REALLY ARE? Rodrigo Freddi, Rubens Park, Mauricio Cordeiro, Luiz Oliveira, Giuliano Guglielmetti, Rafael Coelho, Wellington Andraus, and William Nahas Rodrigo FreddiRodrigo Freddi More articles by this author , Rubens ParkRubens Park More articles by this author , Mauricio CordeiroMauricio Cordeiro More articles by this author , Luiz OliveiraLuiz Oliveira More articles by this author , Giuliano GuglielmettiGiuliano Guglielmetti More articles by this author , Rafael CoelhoRafael Coelho More articles by this author , Wellington AndrausWellington Andraus More articles by this author , and William NahasWilliam Nahas More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1909AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES During a long time the patients with tumoral thrombus in renal vein and in the inferior vena cava were staged at the same group in the TNM classification (T3b). Only in the 2009 revision of the TNM system they were separated in 2 different groups - T3a for renal vein involvement and T3b for inferior vena cava involvement, Our intent is to ratify the difference between these 2 groups and to analyze factors that could interfere in the mortality of these patients. METHODS Between 2004 and 2014, 1163 nephrectomys for renal cancer were performed in our service. Reviewing the records of these patients, we identified 64 patients with tumor thrombectomy - 34 with renal vein thrombus and 30 with inferior vena cava thrombus. We compared these 2 groups and analyzed some clinical and pathological factors that could interfere in the prognosis of those patients. RESULTS In the renal vein thrombus group the mean follow-up was 41 months and the median survival was 42,5 months. In the inferior vena cava group the mean follow-up was 24 months and the median survival was 18 months. The difference in median mortality was statiscally significant (p 0,0003) Patients with inferior vena cava thrombus had a mortality rate 3.5 times higher than the patients with renal vein thrombus. In the same analysis, presence of metastasis, lymph node involvement, perirenal fat invasion, Fuhrman stage and histological subtype were not associated with higher mortality rates. CONCLUSIONS The five-year survival is very higher in the patients with renal vein thrombus when compared with then patients with inferior vena cava thrombus, confirming the need to keep these 2 groups in different classifications in the TNM system. There was no other factors impacting in the survival rate of these patients, not even the presence of metastasis at the diagnosis. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e25 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Rodrigo Freddi More articles by this author Rubens Park More articles by this author Mauricio Cordeiro More articles by this author Luiz Oliveira More articles by this author Giuliano Guglielmetti More articles by this author Rafael Coelho More articles by this author Wellington Andraus More articles by this author William Nahas More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...