Abstract

Introduction: Stereotactic radiosurgery (SRS) has become an increasingly important treatment modality for a variety of neurosurgical conditions including AVMs, primary and metastatic tumors, and even movement disorders. Radiosurgery may be complicated by post-treatment neurological deficit secondary to radiation necrosis and cranial nerve injury. We now report 2 cases of moyamoya syndrome which developed in patients treated with SRS for AVMs. While progressive ischemic vasculopathies have been described in patients following conventional radiation therapy, this is the first report of this complication following SRS. Methods: A review of our series of cases of moyamoya syndrome found 2 patients who had received SRS for AVM. Hospital and office charts as well as all radiographic studies were reviewed. Results: Patient 1 (31 year old female) was born with a left hemiparesis. A large (>5 cm) fronto-parietal AVM was diagnosed following a seizure at age 21. She was subsequently treated with Bragg-peak radiosurgery. She...

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