Abstract
Editorial summaryPathogen genomic analysis is a potentially transformative new approach to the clinical and public-health management of infectious diseases. Health systems investing in this technology will need to build infrastructure and develop policies that ensure genomic information can be generated, shared and acted upon in a timely manner.
Highlights
Pathogen genomic analysis is a potentially transformative new approach to the clinical and public-health management of infectious diseases
The promise of pathogen genomics Whole-genome sequencing (WGS) of specific pathogens and metagenomic sequencing of communities of microbes have been used in a wide range of clinical and epidemiological research investigations of infectious disease
Metagenomics has been successfully used to characterise the strain of Shiga-toxin-producing Escherichia coli (STEC) O104:H4 that was responsible for a pan-European outbreak [4] and in a diagnostic context to identify rare neurological infections [5] and transplant-related infections [6]
Summary
Pathogen genomic analysis is a potentially transformative new approach to the clinical and public-health management of infectious diseases. Moves are afoot within a number of health systems to establish pathogen WGS infrastructure and services to meet the ongoing need to manage infectious disease at a national and international level.
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