Abstract
Schistosomiasis is a water borne parasitic disease of global importance and with ongoing control the disease endemic landscape is changing. In sub-Saharan Africa, for example, the landscape is becoming ever more heterogeneous as there are several species of Schistosoma that respond in different ways to ongoing preventive chemotherapy and the inter-sectoral interventions currently applied. The major focus of preventive chemotherapy is delivery of praziquantel by mass drug administration to those shown to be, or presumed to be, at-risk of infection and disease. In some countries, regional progress may be uneven but in certain locations there are very real prospects to transition from control into interruption of transmission, and ultimately elimination. To manage this transition requires reconsideration of some of the currently deployed diagnostic tools used in surveillance and downward realignment of existing prevalence thresholds to trigger mass treatment. A key challenge will be maintaining and if possible, expanding the current donation of praziquantel to currently overlooked groups, then judging when appropriate to move from mass drug administration to selective treatment. In so doing, this will ensure the health system is adapted, primed and shown to be cost-effective to respond to these changing disease dynamics as we move forward to 2020 targets and beyond.
Highlights
Schistosomiasis is a waterborne infection and is one of the most common parasitic diseases in the world, and is of public health global importance [1]
It is recommended that schistosomiasis endemic countries progressively scale-up their objective from control of morbidity to elimination as a public health problem, and interruption of transmission
In the mapping design for schistosomiasis, the health district is the implementation unit, and a subsample of up to Because of the highly focal distribution of the disease, there is a need for more accurate mapping to deepen the understanding of the distribution of schistosomiasis and snails in the country, which should guide programme decision making for mass drug administration
Summary
Schistosomiasis is a waterborne infection and is one of the most common parasitic diseases in the world, and is of public health global importance [1]. The summary of the global update of preventive chemotherapy implementation in 2015 revealed a significant improvement in the treatment coverage, reaching for schistosomiasis up to 41.8 and 40.8% for school-aged children at the global and African regional levels, respectively.
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