Movement-related neuromagnetic fields in preschool age children

Abstract

Event Abstract Back to Event Movement-related neuromagnetic fields in preschool age children Douglas Cheyne1, 2*, Cecilia Jobst1, Graciela Tesan3, 4, Stephen Crain4, 5 and Blake Johnson4 1 Hospital for Sick Children, Neurosciences and Mental Health, Canada 2 University of Toronto, Medical Imaging, Canada 3 Macquarie University, Department of Cognitive Science, Australia 4 Macquarie University, ARC Centre of Excellence in Cognition and Its Disorders, Australia 5 Macquarie University, Department of Linguistics, Australia We report the first recordings of movement-related brain activity in preschool age children using a custom-sized pediatric MEG system. A videogame-like task was used to generate self-initiated right or left index finger movements in seventeen healthy right-handed preschool age children (8 female, ages 3.2 to 4.8 years). Using beamformer source analysis and a surrogate MRI normalization procedure, we were able to identify sources of movement-related brain activity, including pre-movement motor fields and transient movement-evoked fields (MEFs), in the contralateral sensorimotor cortex. However, both motor fields and movement-evoked fields demonstrated different timing and polarity in comparison to adults, similar to that observed for somatosensory and auditory evoked responses during early development. In addition, the timing and frequency of movement induced oscillatory activity differed from the typical adult pattern, with greater co-modulation of mu and beta rhythms at lower peak frequency. Transient high-frequency gamma oscillations in motor cortex were observed at movement onset, similar to that observed in adults, but with some children also showing bursts in the lower gamma range. We also observed a movement-locked activation of the right superior temporal gyrus for both left and right movements, which has not been previously reported in adults. These findings indicate that basic sensorimotor activation patterns are markedly different in children prior to 5 years of age, and are undergoing maturational changes from early to later childhood. Such changes have implications for both early brain development and our understanding of the role of this activity in normal and abnormal cognitive development. Supported by grants from the Australian Research Council to S.C. and B.J. (LEO668421, LP0669471), CE110001021), NSERC of Canada to D.C. (RGPIN 184018) and the Kanazawa Institute of Technology. Keywords: MEG, Children, gamma oscillations, mu rhythm, beamforming, early development, sensorimotor oscillations, movement-related fields Conference: XII International Conference on Cognitive Neuroscience (ICON-XII), Brisbane, Queensland, Australia, 27 Jul - 31 Jul, 2014. Presentation Type: Poster Topic: Motor Behaviour Citation: Cheyne D, Jobst C, Tesan G, Crain S and Johnson B (2015). Movement-related neuromagnetic fields in preschool age children. Conference Abstract: XII International Conference on Cognitive Neuroscience (ICON-XII). doi: 10.3389/conf.fnhum.2015.217.00195 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 19 Feb 2015; Published Online: 24 Apr 2015. * Correspondence: Dr. Douglas Cheyne, Hospital for Sick Children, Neurosciences and Mental Health, Toronto, Canada, douglas.cheyne@utoronto.ca Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Douglas Cheyne Cecilia Jobst Graciela Tesan Stephen Crain Blake Johnson Google Douglas Cheyne Cecilia Jobst Graciela Tesan Stephen Crain Blake Johnson Google Scholar Douglas Cheyne Cecilia Jobst Graciela Tesan Stephen Crain Blake Johnson PubMed Douglas Cheyne Cecilia Jobst Graciela Tesan Stephen Crain Blake Johnson Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.