Abstract
Introduction: There have been conflicting results whether or not movement-related neural activity is lateralized in the human basal ganglia. Two recent studies have reported an increase in neuronal gamma (60–80Hz) activity in local field potential (LFP) recordings from the subthalamic nucleus of treated Parkinson's disease patients and from the internal globus pallidus of dystonia patients contralateral to the moved hand, suggesting a physiological nature of this asymmetric pattern of gamma reactivity. Here, we investigated the movement-related gamma response in the thalamus in patients undergoing thalamic DBS for tremor to further explore its possible physiological nature.
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