Abstract

Experiments examining the effect of ethyl carbamate and butyl carbamate on mammary carcinogenesis are reported. Virgin female C3H mice receiving ethyl carbamate or butyl carbamate showed a higher incidence of tumors than the controls. The action of ethyl carbamate was the same when given in massive or fractionated dose but a massive dose shortened the latent period of tumor development. Simultaneous administration of ethyl carbamate and butyl carbamate had a summational effect. Administration of croton oil to animals receiving ethyl carbamate did not provoke the appearance of skin tumors. A higher number of metastases was observed in animals bearing breast tumors when ethyl carbamate or butyl carbamate was administered.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.