Abstract
Experiments examining the effect of ethyl carbamate and butyl carbamate on mammary carcinogenesis are reported. Virgin female C3H mice receiving ethyl carbamate or butyl carbamate showed a higher incidence of tumors than the controls. The action of ethyl carbamate was the same when given in massive or fractionated dose but a massive dose shortened the latent period of tumor development. Simultaneous administration of ethyl carbamate and butyl carbamate had a summational effect. Administration of croton oil to animals receiving ethyl carbamate did not provoke the appearance of skin tumors. A higher number of metastases was observed in animals bearing breast tumors when ethyl carbamate or butyl carbamate was administered.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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