Motor Neuron Disease with Descending Paralysis in a 55-Year-old African Man: A Review of the Pattern of Presentation

Abstract

Motor neuron diseases (MNDs) are neurodegenerative disorders that are distinguished by muscle wasting and loss of muscle strength following the gradual deterioration and death of Motor Neurons. Amyotrophic lateral sclerosis (ALS) is the commonest among MNDs. These diseases are untreatable, with limited disease-modifying therapy options. There is a paucity of research on MNDs in Sub-Saharan Africa, particularly, molecular and genetic-based studies are deficient. We present a case report of a 55-year-old African with a descending form of paralysis of Motor Neuron disease