Abstract

AbstractMotoneurone models were developed by modifications of the Frankenhaeuser‐Huxley equations (1964) for voltage clamp data amphibian nerve fibre. The major modifications were: (i) that the subthreshold sodium inactivation was decreased, and (ii) that the Frankenhaeuser‐Huxley model was provided with a long‐lasting after‐hyperpolarization due to potassium permeability changes. Besides, model versions were developed that also had passive membrane properties (e. g. a resting membrane time constant) similar to those of spinal motoneurones. For various model versions, single spikes and the associated afterpotentials were shown in the present paper. The main aim was to use the motoneurone models for studies of repetitive impulse firing. This will be done in a subsequent paper (Kernell and Sjoholm 1972).

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