Abstract

The computer simulations of EPR spectra of spin labels, selectively bound to the Torpedo marmorata electric-organ-membrane-bound acetylcholinesterase active site, were used to select between isotropic Brownian diffusion and anisotropic fast libration of the piperidine ring. For both representative models a better fit was obtained for the libration of the piperidine ring of the label as reflected by the EPR spectrum.

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