MOTILITY OF THE ILEUM AND ITS RELATION TO DIARRHEA AFTER SUBTOTAL COLECTOMY

Abstract

In dogs, subtotal colectomy with ileoproctostomy is followed by severe diarrhea and shortening of passage time. However, they gradually subside postoperatively . These patho-physiological adaptations were studied from the viewpoint of ileal motility on 23 adult mongrel dogs. Electrcphysiological, morphological and X-ray cinematographical studies were performed 1, 4, 12, and 24 weeks postoperatively.Electrical activity of the terminal ileum, especially, spike potential was recorded from immidiate cranial portion (Portion A) of the anastomosis and 30cm cranially away (Portion B). In each portion, much increased frequency of spike was observed in one week postoperatively, and after this period frequency of decreased gradient was recognized.In Portion A, increasing hypertrophy of internal circular and external longitudinal muscle coat was observed. In Portion B, however, no remarkable changes were obtained.X-ray cinematography demonstrated much increased peristalsis of the ileum and the complexed picture in Portion A consisting of iso-and-antiperistalsis in one week postoperatively. Then, decreased gradient of ileal peristalsis was observed markedly between Portion A and B.In conclusion, we perceived that functional hypertrophy of the ileal muscle coat caused by hyperperistalsis on the anastomosis is an important factor for decreased peristalsis of the terminal ileum and such phenomenon is advantageous for the process of recovery from diarrhea the shortening of passage time.