Abstract
I read with interest the commentary on prevention of chronic hepatitis B virus infection.1 An important issue that was not discussed concerns the use of the hepatitis B vaccine and transmission of the newly recognized acquired immune deficiency syndrome (AIDS). The etiology of AIDS is unknown. AIDS occurs among the populations that donate plasma for hepatitis B vaccine manufacture.2,3 The safety of plasma donated for hepatitis B vaccine by persons with chronic hepatitis B who may have unrecognized or early AIDS is not known.
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