Mosquitocidal Chips Containing the Insect Growth Regulator Pyriproxyfen for Control of Aedes aegypti (Diptera: Culicidae).

Kristen C Stevens,Philip G Koehler,Roberto M Pereira

doi:10.3390/ijerph16122152

Kristen C Stevens, Philip G Koehler + Show 1 more

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https://doi.org/10.3390/ijerph16122152

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Abstract

Aedes aegypti were exposed to water treated with mosquitocidal chips containing the insecticide pyriproxyfen in a polymer formulation. Chips were tested under different conditions; different water volumes, in containers made of different material, and in water with different levels of organic matter. Treated chips caused 100% mortality of Ae. aegypti during their pupal stage independent of size or type of container, and the mount of organic matter contained in the water to which the mosquito larvae were exposed. When mosquitocidal chips were used in >25% of the oviposition containers within their cages, there was a significant control of the mosquito populations. Mosquitocidal chips worked in different environments, caused significant mosquito population decreases, and were effective in controlling Ae. aegypti.

Highlights

Aedes aegypti, the yellow fever mosquito, is considered one of the world’s greatest health threats.One class of chemicals commonly used to control Ae. aegypti larvae are insect growth regulators (IGRs) [1,2]
In mosquito mortality (F = 96.74, df = 4, p ≤ 0.0001) when mosquitocidal chips were used in different water volumes and a significant interaction between water volume and time (F = 17.05, df = 12, p ≤ 0.0001)
Aedes aegypti use different types of containers with varying water volumes [9,15], but the mosquitocidal chips were effective in water varying volumes because the mosquitocidal chips were designed to release 10 PPB pyriproxyfen in 1000 mL of water

Summary

Introduction

One class of chemicals commonly used to control Ae. aegypti larvae are insect growth regulators (IGRs) [1,2]. IGRs disrupt insect growth and reproduction by interfering with insect development [1,2,3]. Juvenile hormone analogs (JHAs) disrupt insect development and prevent insects from reaching the adult stage by providing increasing juvenile hormone in insects at a time these compounds do not normally occur [2,3], preventing proper mosquito development. Pyriproxyfen, a juvenile hormone analog, is a relatively stable chemical which results in insects being unable to molt to the adult stage [3,4]. It is approved by the U.S Environmental Protection

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