Mosquito larvicidal efficacy of methanolic extract from seeds of Datura inoxia Mill against Aedes aegypti (Linn.) with insight into GC-MS analysis

Abstract

The GC-MS analysis revealed the presence of 38 components, the major chemical constituents in the extract were atropine (20.55%), cis-13, 16-docasadienoic acid (19.73) n-hexane (15.67%), 1-chloro-1-fluoro ethane (6.84%), 9, 12-octadecadienoic acid (5.10%), lup-20(29)-en-3-ol, acetate (5.01%), scopolamine (2.87%). Bioassay experiments using methanolic extract from seeds of Datura inoxia Mill showed significant larvicidal activity against third instar larvae of Aedes aegypti with LC50 and LC90 values of 72.44 and 275.42 ppm, respectively.