Moschamide: An unusual alkaloid from the seeds of Centaurea moschata

Abstract

8-formamido-2-(4-hydroxy-3-methoxyphenyl)-2,2a,5,6-tetrahydro-3 H-furo[2,3,4- kl][3]benzazocine-3,7(4 H)-dione (named: moschamide), a novel alkaloid, has been isolated from the seeds of Centaurea moschata (Compositae). The structure of this compound has been determined primarily by extensive 1D and 2D NMR spectroscopic analysis, notably, 1H, 13C PENDANT, COSY45, NOESY, HMBC and HMQC.