Mortality Trend of Hodgkin Lymphoma in Ecuador from 2000 to 2019

Abstract

Introduction. Globally, the incidence of Hodgkin lymphoma (HL) increased from 1990 to 2017, presenting two incidence peaks regarding age, at 20–39 years, and 60 years or more. However, there is limited information about the mortality of this disease in the Ecuadorian population. This study aims to present the mortality trend of HL in Ecuador from 2000 to 2019. Methods. We performed an observational study, reporting the crude death rates by HL in the Ecuadorian population from 2000 to 2019, and its mortality trend analysis. Data were extracted from governmental databases published by the Ecuadorian National Institute of Statistics and Census (INEC). Results. From 2000 to 2019, INEC registered 862 deaths of patients with HL. From them, 355 (41.18%) were female, and 699 (81.09%) resided in urban areas, with an average age of 54.61 years. During the period studied, the mortality rates by HL in Ecuador presented a significant increasing trend (p=0.037), in which 2019 and 2018 were the years with the highest death rate (0.38 by 100,000 inhabitants), whereas 2001 and 2007 had the lowest death rate (0.20 by 100,000 inhabitants). Regarding age, we found a bimodal distribution of cases with two peaks in the 2nd and 7th decades of life. Conclusion. In this study, we found the highest mortality rate of HL in 2018 and 2019, with a significant increasing trend since 2000. Regarding age, we found two highest mortality peaks, which correspond to the 2nd and 7th decades of life, similar to other studies in the region.