Mortality secondary to acute gastric variceal bleeding: a further prediction of outcome by acute kidney injury

Abstract

Bleeding from the rupture of esophageal varices is one of the most serious complications of portal hypertension. In fact, up to 20% of patients die acutely or within 6 weeks after the bleeding episode (1). Advanced Child-Pugh class, an elevated hepatic venous pressure gradient (HVPG, ≥20 mmHg), high model for end-stage liver disease (MELD) score values are the main predictors of this poor outcome (2-4). Therefore, many studies evaluated how to prevent variceal bleeding (or rebleeding) in cirrhosis.