Abstract
While the death rate associated with infective endocarditis (IE) remains high, the parameters for predicting mortality are poorly defined. Through a retrospective study of 100 patients with IE based on Duke criteria, our group evaluated the clinical and echocardiographic factors that most strongly correlate with intrahospital mortality. The study included patients with native valves and prosthetic valves as well as patients with congenital cardiac disease. The results were obtained using the chi-square and Fisher exact tests. We observed a positive relation between mortality and age (P = 0.005), anemia (P = 0.047), neurological events (P = 0.0006), Janeway lesions (P = 0.0032), number of abnormalities on echocardiography (P = 0.047) and a tendency for a higher mortality related to cardiac heart failure (P = 0.105), renal insufficiency (P = 0.093), arthritis (P = 0.063), mitral valve involvement (P = 0.062), surgical indication (P = 0.076), and cardiac abscess (P = 0.081). In conclusion, age, anemia, neurological events, number of echocardiographic abnormalities and Janeway lesions are strongly correlated with an increased mortality risk. The presence of cardiac heart failure, renal insufficiency, arthritis, mitral valve involvement, abscess and surgical indication show a tendency for the same correlation.
Highlights
Cardiac surgery with cardiopulmonary bypass (CPB) is a recognized trigger of systemic inflammatory response, usually related to postoperative acute lung injury (ALI)
The objective was to evaluate the characteristics of Chest pain (CP) in patients with acute aortic dissection (AAD) admitted in a chest pain unit (CPU)
Patients and methods We evaluated in a cross-sectional and prospective study patients admitted in a CPU, between March 1997 and May 2001, with diagnosis of AAD
Summary
Cardiac surgery with cardiopulmonary bypass (CPB) is a recognized trigger of systemic inflammatory response, usually related to postoperative acute lung injury (ALI). Few studies exist analysing the handling of acute respiratory insufficiency with invasive mechanical ventilation (IMV) and its correlation with mortality among the elderly intensive care unit (IUC) patient population. In Brazil, most patients with TBI are managed in general ICUs. The results of the treatment of patients admitted to nonspecialized ICUs must be compared with those obtained in neurosurgical ICUs. An acute confusional state (ACS) has been a frequent finding in patients undergoing cardiac surgery (CS), which, according to the literature, has resulted in a greater number of complications and in an increase in hospitalization and length of stay in the intensive care unit (ICU). The mortality of elderly patients who are admitted to intensive care units (ICU) has been the aim of some recent studies. Drugs that modulate such phenotypic alterations may be useful in the control of these and other clinical situations
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