Mortality in adult patients with Eisenmenger Syndrome: 5-Years perspective

Abstract

The number of congenital heart disease (CHD) patients worldwide is increasing. Eisenmenger syndrome continues developing in patients who, for various reasons, did not undergo early surgery for CHD but may also occur in previously operated patients. When Eisenmenger syndrome develops, repair of the underlying defect is contraindicated. We have previously published the largest to date, international study providing information on contemporary outcomes of Eisenmenger syndrome and identifying factors associated with higher risk of death. We have, herewith, performed further indepth analysis of our data, culminating to an absolute predicted 5-year mortality table for patients with ES, an important aid to optimal care. Selection criteria for lung or heart lung transplantation in Eisenmenger syndrome, in the absence of absolute mortality estimates for conservative management, have been uncertain and this is where our novel risk stratification tool should contribute.