Mortality from malignant bowel obstruction in hospitalized U.S. cancer patients.

Abstract

9626 Background: Malignant bowel obstruction (MBO) affects an estimated 3 - 15% of cancer patients globally, with a mean survival rate no longer than 4 weeks in inoperable MBO. We assessed predictors of survival and the influence of treatment modality in hospitalized MBO patients in the US. Methods: Data were obtained from all US states that contributed to the Nationwide Inpatient Sample (NIS) by Agency for Health Care Research and Quality in 2006 and 2010. MBO diagnoses and treatment variables were identified using Clinical Classification Software code based on ICD9 and CPT codes. Univariate and multivariate analyses were performed with a logistic model, weighted chi-square test, and a generalized linear model with the use of generalized estimated equation. Initial analysis in the 2006 NIS data was validated in the 2010 NIS data. Results: 942,014 and 1,103,528 eligible MBO patients were identified in 2006 and 2010 respectively. The in-hospital mortality was 24.5% in 2006, decreasing to 21.4% by 2010. The...