Abstract
Aim:To evaluate associations between survival and glycemic control in age-matched patients with endometrial or ovarian cancer, with/without diabetes mellitus (DM).Patients & methods:Patients with newly diagnosed ovarian or endometrial cancer with and without DM were compared.Results:The study included 84 patients with ovarian cancer (28, DM); 96 with endometrial cancer (48 with, 48 without DM). DM patients did not have worse overall or progression-free survival than non-DM patients. Glycemic control was not associated with either cancer.Conclusion:There was no association between DM and survival for patients with uterine or ovarian cancer. In addition, there was no association between uterine and ovarian cancer and glycemic control. Additional studies to confirm these observations in larger populations are required.
Highlights
Data are lacking in the literature regarding the impact of ovarian and uterine cancer on diabetes mellitus (DM) and the impact of DM on survival of patients with ovarian or uterine cancer
BMI was significantly different between patients with and without DM (p < 0.001)
For patients with ovarian cancer, the mean glucose level within 1 year of cancer diagnosis was higher for patients with DM than for patients without DM (130.3 vs 113.8 mg/dl)
Summary
To evaluate associations between survival and glycemic control in age-matched patients with endometrial or ovarian cancer, with/without diabetes mellitus (DM). Lay abstract: The aim of this study was to evaluate the effect of diabetes mellitus (DM) on survival of patients with ovarian or uterine cancer and to determine whether ovarian and uterine cancer affected glycemic control. The purpose of this study was to evaluate, using matched data sets, the interaction between survival, recurrence and glycemic control in separate cohorts of patients with endometrial or ovarian cancer, with and without DM
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