Abstract
The Morris water maze is widely used to study spatial memory and learning. Animals are placed in a pool of water that is colored opaque with powdered non-fat milk or non-toxic tempera paint, where they must swim to a hidden escape platform. Because they are in opaque water, the animals cannot see the platform, and cannot rely on scent to find the escape route. Instead, they must rely on external/extra-maze cues. As the animals become more familiar with the task, they are able to find the platform more quickly. Developed by Richard G. Morris in 1984, this paradigm has become one of the "gold standards" of behavioral neuroscience.
Highlights
The Morris water maze is widely used to study spatial memory and learning
Animals are placed in a pool of water that is colored opaque with powdered non-fat milk or non-toxic tempera paint, where they must swim to a hidden escape platform
Facing the wall of the pool, the animal handler will place the animal in the water, and will step back from the pool and sit in a designated spot while the animal performs the maze task
Summary
Place the escape platform in the center of the pool During training, it must be exposed, one inch above the water. The water maze is ready for training the animals. 1. For the water maze training, the platform should be in the center of the pool and exposed one inch above the surface, so the animal knows that it’s there. Let the animal sit on the platform for 15 seconds If it falls or jumps off, gently guide it back. This will train the animal that it must stay on the platform to be rescued from the pool. Repeat the three-trial training process for all the animals consecutively. 8. that the animals are trained, they are ready to perform the water maze test
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