Abstract
Background: Metabolic syndrome is the challenge of this era; diseases are initiated with the abnormal functioning liver. This study aims to evaluate the effects of HFD on liver anatomy and to study the morphological changes with its histological findings
 Methodology: 50 male albino rats were acclimatized in the animal house of DUHS, divided into 5 groups (GP). GP 1 was on a standard diet for 6 weeks, GP 2 was on HFD for 6 weeks, GP 3, GP 4, and GP 5 were on HFD for 6 weeks. They were treated with ginseng root extract in doses of 100mg/ml, 200mg/ml and 400 mg/ml for 6 weeks. After 12 weeks, GP3, GP4, and GP 5 were dissected, and the liver was isolated for histology and micrometry. Blood was drawn and sent for LFT to correlate morphological changes with enzymes. 
 Results: Rats on a high-fat diet developed fatty liver with altered LFT. The treated group showed a reversal of changes in morphology and LFT in a dose-dependent manner.
 Conclusion: The morphometric analysis revealed that fatty accumulation in liver cells deranges the liver function leading to metabolic syndrome. Ginseng root extract helps in depleting fatty accumulation in the liver.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Endorsing Health Science Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
