Abstract

The principles of morphogenesis of Ammon's horn of the neonatal rat hippocampus in tissue culture (area CA1-2) were studied by light-optical and electron-microscopic methods. Analysis of 5-, 12-, and 21-day cultures revealed maturation of the hippocampal pyramidal cells in vitro, the development of a protein-synthesizing system, and synaptogenesis. The synchronous development of the synaptic structures, of the protein-synthesizing system of the cell, and of electrogenesis suggests that these are interconnected factors.

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