Abstract
Mastocytoma is a kind of cutaneous tumour consisting of a great number of variously differentiated mastocytes. In dogs, they make 15-20% out of all cutaneous tumours, and are also considered to be potentially malignant skin tumours. They appear mosly in the region of abdomen (50-60%), less frequenly at limbs (25-40%) and very rarely at head and neck skin (10%). This work is a retrospective analysis of all diagnosed mastocytoma during the period from 2004. to 2012. at the Department of Pathology, Faculty of Veterinary Medicine in Belgrade. Biopsy material was exposed to histopathological examination. Tissue cuttings of 3-5 ?m thick were dyed by HE method and TB method. Questionnaire on the frequency of mastocytoma was carried out in 40 veterinary policlinics in Belgrade. During the specified period, 65 cases of mastocytoma were diagnosed. They participated in 9.46% of all skin tumours. They were located at head skin, abdomen skin and limbs skin as well, and found in various dogs breeds. Mastocytomas were diagnosed in 25 policlinics in Belgrade. They were of nodose, irregular, verrucose and polypose shapes with numerous secondary alterations. Mastocytoma represented most frequent hematopoietic and ?round cell? diagnosed tumours. Most frequently they were located at limbs. Predisposed breeds are Golden Retriever and half-breed. Nodose form with expansive growth and secondary alterations such as inflammations was prevailing.
Highlights
Mastocitomi su tumori koe gra|eni od velikog broja razli~ito diferentovanih mastocita
Pojavljuju se na koi trupa (50-60%), ne{to re|e na ekstremitetima (25-40%) i najre|e na koi glave i vrata (10%)
Prema ovom sistemu mastocitomi su gradirani na tri stepena na osnovu slede}ih kriterijuma: stepena diferencijacije, celularnosti, }elijske morfologije, mitoti~kog indeksa i reakcije veziva
Summary
Godine na Katedri za patologiju, Fakulteta veterinarske medicine u Beogradu. Stevanovi} i sar.: Morfologija, gradacija i u~estalost mastocitoma kod pasa. Mastocitomi su tumori gra|eni od velikog broja razli~ito diferentovanih mastocita (Aleksi}-Kova~evi} i sar., 2005). Kod pasa, ~ine 15-20% svih tumora koe i ujedno predstavljaju naj~e{}e maligne ili potencijalno maligne tumore koe. Na osnovu ranijih izu~avanja na Katedri za patologiju Fakulteta veterinarske medicine u Beogradu u periodu od 1999. Tumori su naj~e{}e bili lokalizovani na koi ekstremiteta, glave i trupa (Aleksi}Kova~evi} i sar., 2005). U navedenom periodu na Katedri za patolo{ku morfologiju Fakulteta veterinarske medicine u Beogradu nisu dijagnostikovani ekstrakutani mastocitomi kod pasa. Broj mastocitoma na osnovu retrospektivne analize upore|en je sa brojem mastocitoma koji su dijagnostikovani u laboratorijama za patologiju Fakulteta veterinarske medicine u Ljubljani, Zagrebu i Sarajevu, uzimaju}i u obzir dijagnostikovane mastocitome u poslednje 3 godine (Tabela 2).
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