Abstract
The current study was conducted to identify the effects of different doses of Arabic coffee, black tea and Coca-Cola syrup on the possibility of birth defects in Swiss white mice embryos. (25) pregnant female mice were used in the study, divided into five experimental groups, including the control group dosed with distilled water, and four experimental groups were dosed with concentrations (4000-2500-2000-1000) mg/kg body weight for Arabic coffee and black tea and (2,3,4,6 ml/kg) for Coca-Cola syrup; once a day, from the seventh day until the eighteenth day of pregnancy. The results of the current study showed cases of abortion and fetal death at varying degrees and many abnormalities in white mouse embryos due to the different concentrations of the beverages used were characterized by the appearance of elongated and enlarged embryos. The elongation and deformation of the fetus, And the embryos mutated. Small embryos folded like a ball and curved in the shape of letter C, and the severity of the deformities increased by the appearance of mutated embryos resembling the body of a fish and deformed embryos similar to a water mermaid and not fully developed and the appearance of the head in the shape of a blurred triangle, as well as forward with a pointed end resembling a bird's beak, and brain deformation through depression in the posterior cranial region of the skull, and for the first time a new deformation is a cerebral Meningomyelocele in the form of a cystic tumor in the posterior brain region.
Highlights
In most countries around the world, social beverages are one of the most popular drinks, but how does it look when consumed in large amounts during pregnancy, causing miscarriages, damages, deformities, and birth defects (AL-Rasheedi,2009)
The results of the current study showed miscarriage and fetal death at varying degrees in experimental groups dosed with the drinks used, as observed when aqueous solution of Arabic coffee was administered at a concentration of 4000 mg/kg body weight; the rate of abortion was 33
The experimental group fed an aqueous solution of black tea at a concentration of 4000 mg/kg of body weight had a 29 percent miscarriage rate
Summary
In most countries around the world, social beverages are one of the most popular drinks, but how does it look when consumed in large amounts during pregnancy, causing miscarriages, damages, deformities, and birth defects (AL-Rasheedi,2009). Commercial advertisements in various media outlets are widely observed by companies and factories that produce such drinks strikingly in order to highlight their nutritional importance, which has caused a large number of people to over-consume them without any reference to the negative effects of unusually using them. Caffeine crosses the placental wall to the fetus and increases the likelihood of spontaneous abortion, as well as a lack of fetal growth and congenital malformations within the womb, which sometimes leads to fetal loss and death (Weng and Odouli,2008). There are very few studies on the effect of caffeine beverages on fetus levels and fetal development, especially during pregnancy (Bech et al.,2005). Very small studies (Bech et al.,2007)
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