Abstract
The solution to the problem of evolution has proven refractory to experimentation-how fish have evolved into Man phylogenetically, for example-because evolution is thought to be due to random mutations, obviating the opportunity to test such a mechanism, leaving only correlations and associations, which do not show causation. Ideally, there would be some comparable process that could be exploited in order to deconvolute evolution, but none had been forthcoming up until now, having been introduced to Knot Theory, a subheading of Topology. Topology concerns itself with how geometric objects maintain themselves under continuous deformations. Knot Theory is the study of mathematical knots, inspired by the knots that occur in everyday life. It occurred to us that since knots tie things together, they are similar in kind to the cell-cell signaling mechanisms that tie physiologic traits together during development, culminating in physiology, tied together by homeostasis.
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