Morphological features of structural rearrangement of thrombi in patients with occlusive-stenotic diseases of the main arteries of the lower extremities

Abstract

Annotation. According to the set goal of the work, we analyzed the results of morphological studies of blood clots that formed in the main arteries at different time intervals in patients with occlusive-stenotic diseases of the arteries of the lower extremities as a consequence of obliterating atherosclerosis. The material of the study was fragments of the arteries of 10 patients whose lumen was closed by blood clots taken during open surgical interventions on different arterial segments, and in 8 cases, autopsy material of thrombosed arteries of the femoral and popliteal segments was selected. The histological research method is applied. It is established the thrombus located in the main artery undergoes structural organization in the process of its changes. In addition, the thrombus and its changes in organization, together with the severity of the atherosclerotic plaque, leads to vessel stenosis and significant local or systemic hemodynamic changes, and thus determines the indications for a particular type of surgery for occlusive-stenotic diseases of the main arteries of the lower extremities.