Abstract

An attempt was made (1) to fractionate microcrystalline cellulose (MCC) particles of Avicel® PH-101 (PH grade) and Ceolus® KG-801 (KG grade) into four sieve fractions by using an air-jet sieve and (2) to disclose effects of morphology of the particle on tablet tensile strength, T. The morphology of MCC particles is one of the most important factors affecting T. T increased with an increase in the ratio of L/ D for particles ( L, length; D, width). KG grade consists of a larger number of rod-shaped particles than PH grade, giving significantly higher compressibility than PH grade.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.