Abstract

We focused on the investigation of the influence of carboxylic acid additives on the morphology of hydroxyapatite (Ca10(PO4)6(OH)2, HAp) particles synthesized by a homogeneous precipitation method. Three types of carboxylic acids with different number of carboxyl groups, that is, acetic acid, succinic acid and citric acid, were used as additives to control the nucleation, growth and alignment of HAp crystals. The powder properties of resulting particles were examined by powder X-ray diffractometry, fourier-transform infrared spectroscopy, and scanning electron microscopy. All resulting particles were identified to be single-phase carbonate-containing calcium-deficient HAp. The resulting particles synthesized by using acetic acid as an additive were strip-like morphology. In the case of succinic acid addition, the resulting particles exhibited irregular plate-like or spherical morphology. Wheileas, in the case of citric acid addition, the obtained particles became regular spherical shape. These results indicate the numbers of carboxyl groups of carboxylic acid give an influence of the morphology of the HAp particles.

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