Abstract
Biopsies of five patients with Barrett's syndrome were examined by light microscopic, cytochemical and electron microscopic techniques. It was shown that the mucosa in the lower oesophagus lined by columnar epithelium was very similar to the mucosa lining the cardia of the stomach. It is supposed that such esophageal epithelium represents an upgrowth of cardia mucosa as a response to injury of the squamous epithelium of the oesophagus caused by chronic reflux of gastric contents. The occurrence of goblet cells and patches of villous columnar cells was interpreted as intestinal metaplasia.
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Schedule a callMore From: Virchows Archiv. A, Pathology. Pathologische Anatomie
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