MORPHOLOGICAL CHARACTERISTICS OF THE ANTERIOR ABDOMINAL WALL TIS-SUES IN CASES OF IMPLANTATION OF POLYPROPYLENE MESH WITH PRF MEMBRANE

Abstract

According to the experimental study on Vietnamese pigs after implantation of a polypropylene mesh with PRF membrane into retromuscular space, the results of ultrastructural changes in the cells of muscular aponeurotic layer of abdominal wall were presented. It was proved that on the 14th day of the experiment, inflammatory changes in tissues were expressed significantly less than in cases of the isolated implantation of the polypropylene mesh without PRF membrane. Activation of fibroblasts and signs of fiber structures development around the mesh material increased. In the late experimental period (28 days), at the microscopic and electron-microscopic levels the minor manifestations of inflammatory reaction, improved microcirculation in the area of implantation of the mesh with PRF membrane were found that in turn contributed to the increased activity of fibroblasts and development of collagen fibers around the mesh material. The use of PRF plasma membranes stimulated an active development of new capillaries, improved blood flow, accelerated metabolic processes in tissues, and suddenly increased development of collagen, hyaluronic acid that in turn created favourable environment for a complete integration of the polypropylene mesh into the muscular aponeurotic layer of anterior abdominal wall tissue.