Abstract
A morphological and morphometric study of Guerin carcinoma after cryoablation, local microwave hyperthermia and their combination was performed. Combined exposure was associated with decreased adhesion of tumor cells, increasing the area of necrotic tissue and more expressed angionecrosis compared with independent use of cryoablation or microwave hyperthermia. The results suggest a more expressed degradation of the Guerin carcinoma tumor tissue by the combined use of low temperatures and microwave hyperthermia.
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