Abstract
Exposure of yeast cells to EB produced multiple effects on the cellular organelles; a) changes in the plasma membrane characterized by 75 to 110 nm deep pits; b) polymorphisms of the mitochondria ranging from cup-shaped, ring-shaped, ribbon-shaped, dumbbell-shaped structures to finally the formation of very elongated mitochondria (up to 4.5 μm in length); c) an increase in the length and number of endoplasmic reticulum; d) an increase in the number of cytoplasmic vesicles whose diameter varied between 25 to 45 nm. Furthermore, EB inhibited cytochrome c oxidase and cytochrome b biosynthesis, stimulated cytochrome c biosynthesis and uncoupled oxidative phosphorylation.
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