Morphological approaches in colour vision studies

Abstract

Event Abstract Back to Event Morphological approaches in colour vision studies Akos Lukáts1*, Arnold Szabó1, Viktória Doma1, Gergely Halász1, Agnes Berta1, Pál Röhlich1 and Agoston Szél1 1 Semmelweis University, Department of Human Morphology and Developmental Biology, Hungary The retina of most mammalian species contains two types of cones, one population being sensitive to shorter wavelengths (S-cones), and another one with the a peak sensitivity in the green or in the red part of the spectrum (M/L-cones). In mammals, each cone had been thought to contain only one single type of photopigment. It was not until the early 1990s that photopigment coexpression (dual cones) was first reported. In a well known laboratory animal, the house mouse, the distribution of color cones shows a characteristic division. Whereas in the upper retinal field the ratio of short wave to middle-to-long wave cones falls in the usual range (1:10), in the ventral retinal field M/L-pigment expression is completely missing. In the transitional zone, numerous dual cones are detectable (spatial photopigment coexpression). In some other species without retinal division, dual cones appear during development, suggesting that M/L-cones develop from S-cones. All cones first express the S-opsin only, and some of them continue to do so till adulthood. The rest switch on M/L-opsin production as well, coexpresses both pigments, and then S-opsin disappears from their outer segments (transdifferentiation, transitory photopigment coexpression). Despite intensive studies, little is known about the factors influencing pigment switch. Putative candidates are numerous; their precise role however is mostly unknown. In vitro organotypic retinal culture system is suitable, to investigate the possible regulatory factors of M/L-cone differentiation in Norwegian rats and Syrian golden hamsters. In the latter species, all cones express the M/L-pigment only, an ideal situation for developmental investigations. The retina of both species exhibits full differentiation in vitro, under control conditions. Analyzing and comparing the retinal developments, using different culturing conditions, allow us to study the regulation in two different systems. Grants: Hungarian OTKA #T-73000 and #T-79156. Conference: IBRO International Workshop 2010, Pécs, Hungary, 21 Jan - 23 Jan, 2010. Presentation Type: Oral Presentation Topic: Vision: from the evolution of retinas to the evolution of ideas Citation: Lukáts A, Szabó A, Doma V, Halász G, Berta A, Röhlich P and Szél A (2010). Morphological approaches in colour vision studies. Front. Neurosci. Conference Abstract: IBRO International Workshop 2010. doi: 10.3389/conf.fnins.2010.10.00247 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 05 May 2010; Published Online: 05 May 2010. * Correspondence: Akos Lukáts, Semmelweis University, Department of Human Morphology and Developmental Biology, Budapest, Hungary, lukats@ana2.sote.hu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Akos Lukáts Arnold Szabó Viktória Doma Gergely Halász Agnes Berta Pál Röhlich Agoston Szél Google Akos Lukáts Arnold Szabó Viktória Doma Gergely Halász Agnes Berta Pál Röhlich Agoston Szél Google Scholar Akos Lukáts Arnold Szabó Viktória Doma Gergely Halász Agnes Berta Pál Röhlich Agoston Szél PubMed Akos Lukáts Arnold Szabó Viktória Doma Gergely Halász Agnes Berta Pál Röhlich Agoston Szél Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.