Abstract
Most types of neoplastic lesions seen in human intestinal mucosa were reproduced experimentally in rats and mice after application of 1,2-dimethylhydrazine. Tumor distribution displayed dose-related variations. The relative tumor frequency in the small intestine rose after higher dosage of the carcinogen, with preponderance of the upper segments. Furthermore there were certain species specific differences between rats and mice concerning the tumor distribution within the large intestine.
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