Abstract

Flow diverters (FDs) are designed for the endovascular treatment of complex intracranial aneurysm configurations. From February 2009 to March 2013 28 patients (22 females, 6 males) were treated with FD; mean age was 57 years. Data, including aneurysm features, clinical presentation, history of previous bleeding, treatment, and follow-up results, are presented. Early postinterventional neurological deficits (transient: n = 3/enduring: n = 1) appeared in 4/28 patients (14%), and early improvement of neurological symptoms was observed in 7 patients with previous restriction of cranial nerve function. The overall occlusion rate was 20/26 (77%; 59% after 3 months). 77% achieved best results according to O'Kelly-Marotta score grade D with no contrast material filling (70% of those after 3 months). In 4/6 patients who did not achieve grade D, proximal and/or distal stent overlapping ≥5 mm was not guaranteed sufficiently. During follow-up we did not detect any aneurysm recurrence or haemorrhage. In-stent stenosis emerged as the most frequent complication (4/27; 15%) followed by 2 cases of vascular obliteration (AICA/VA). In conclusion endovascular reconstruction using a FD represents a modern and effective treatment in those aneurysms that are not suitable for conventional interventional or surgical treatment. The appearance of severe complications was rare.

Highlights

  • Low porosity stents play an important role in the effective endovascular treatment of intracranial aneurysms [1,2,3]

  • In addition the Flow diverters (FDs) provides a scaffold for neoendothelialization across the aneurysm neck, which leads to the exclusion of the aneurysm sac from the blood flow in the parent artery and facilitates a sufficient aneurysm occlusion [6]

  • The FD could be placed in a proper position across the parent artery of the aneurysm in 19/28 patients

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Summary

Introduction

Low porosity stents (flow diverter, FD) play an important role in the effective endovascular treatment of intracranial aneurysms [1,2,3]. This device is designed for complex aneurysm configurations, fusiform, or wide-necked aneurysms, especially in cases where conventional coiling is not feasible and in locations where clipping is not a treatment option. In addition the FD provides a scaffold for neoendothelialization across the aneurysm neck, which leads to the exclusion of the aneurysm sac from the blood flow in the parent artery and facilitates a sufficient aneurysm occlusion [6]. The Flow Diversion in Intracranial Aneurysm Treatment (FIAT) [7] and the Large Aneurysm Randomized Trial: Flow Diversion Versus Traditional GDC Based Endovascular Therapy (LARGE) [8]

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