Abstract
Flow diverters (FDs) are designed for the endovascular treatment of complex intracranial aneurysm configurations. From February 2009 to March 2013 28 patients (22 females, 6 males) were treated with FD; mean age was 57 years. Data, including aneurysm features, clinical presentation, history of previous bleeding, treatment, and follow-up results, are presented. Early postinterventional neurological deficits (transient: n = 3/enduring: n = 1) appeared in 4/28 patients (14%), and early improvement of neurological symptoms was observed in 7 patients with previous restriction of cranial nerve function. The overall occlusion rate was 20/26 (77%; 59% after 3 months). 77% achieved best results according to O'Kelly-Marotta score grade D with no contrast material filling (70% of those after 3 months). In 4/6 patients who did not achieve grade D, proximal and/or distal stent overlapping ≥5 mm was not guaranteed sufficiently. During follow-up we did not detect any aneurysm recurrence or haemorrhage. In-stent stenosis emerged as the most frequent complication (4/27; 15%) followed by 2 cases of vascular obliteration (AICA/VA). In conclusion endovascular reconstruction using a FD represents a modern and effective treatment in those aneurysms that are not suitable for conventional interventional or surgical treatment. The appearance of severe complications was rare.
Highlights
Low porosity stents play an important role in the effective endovascular treatment of intracranial aneurysms [1,2,3]
In addition the Flow diverters (FDs) provides a scaffold for neoendothelialization across the aneurysm neck, which leads to the exclusion of the aneurysm sac from the blood flow in the parent artery and facilitates a sufficient aneurysm occlusion [6]
The FD could be placed in a proper position across the parent artery of the aneurysm in 19/28 patients
Summary
Low porosity stents (flow diverter, FD) play an important role in the effective endovascular treatment of intracranial aneurysms [1,2,3]. This device is designed for complex aneurysm configurations, fusiform, or wide-necked aneurysms, especially in cases where conventional coiling is not feasible and in locations where clipping is not a treatment option. In addition the FD provides a scaffold for neoendothelialization across the aneurysm neck, which leads to the exclusion of the aneurysm sac from the blood flow in the parent artery and facilitates a sufficient aneurysm occlusion [6]. The Flow Diversion in Intracranial Aneurysm Treatment (FIAT) [7] and the Large Aneurysm Randomized Trial: Flow Diversion Versus Traditional GDC Based Endovascular Therapy (LARGE) [8]
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