Abstract
Two groups of 14 male Sprague-Dawley rats were given either 1 or 32 days of voluntary access respectively to 7% (v/v) ethanol solution before being injected once with 30 mg/kg of morphine. Alcohol consumption during the subsequent week was suppressed to about the same extent in both cases. Food intake was slightly reduced and water drinking increased in both groups after the morphine injection. The only difference observed between the effects after 1 and 32 days of alcohol access was that in the latter there was a significant negative correlation (r = −.891) between the reductions in alcohol and food consumption. The results suggest that the suppression of alcohol drinking is not dependent upon those factors, such as the ability to show an alcohol-deprivation effect, which develop during prolonged access to alcohol.
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