Abstract
Background: First described by Handmann in 1929, the “Morning Glory Syndrome” is a rare congenital anomaly of the optic papilla whose notable ophthalmoscopic sign is papillary excavation associated with other ocular and/or non-ocular anomalies. Purpose: The main purpose of this study is to report 2 cases of this rare congenital papilla anomaly in 2 young Malian adults diagnosed in the IOTA-University Hospital respectively in January and May 2020. Materials and methods: In our study, we have included two cases of male gender. Results: In the 1st case the defect concerned both papillae. It is also associated with other ocular malformations (bilateral macular reshaping and unilateral cataract), without associated cerebral defects. In the 2nd case, only one papilla was affected by the malformation and there was an absence of associated malformations of other ocular and cerebral structures. Discussion: The Morning Glory Syndrome is part of the group of congenital defects of the optic nerve. It is often referred to as ectasia coloboma of the optical papilla or bindweed flower-like optical papilla because of its similarity to the tropical flower known as “bindweed”. Its exact pathogenesis remains unknown, but it is linked to the poor development of the posterior sclera and lamina cribrosa during gestation. Conclusion: Morning Glory Syndrome through papillary excavation and other associated ocular and/or cerebral malformations may be a threat to vision.
Highlights
Morning Glory Syndrome through papillary excavation and other associated ocular and/or cerebral malformations may be a threat to vision
Purpose of the Study The main purpose of our study is to present our experience on the managing of Morning Glory syndrome in those cases when Morning Glory syndrome causes functional impairment to the patient
Biomicroscopic examination of the adnexae and structures of the anterior segment was normal in the right eye, in the left eye there was subcapsular opacity of the posterior lens
Summary
Rieger (1977) and Pau (1980) corroborated Handmann’s description of other patients [1] It was not until Kindler presented a similar case in 1970 that the name “morning-glory syndrome” was attributed to this congenital optical papilla malformation [1]. First described by Handmann in 1929, the “Morning Glory Syndrome” is a rare congenital anomaly of the optic papilla whose notable ophthalmoscopic sign is papillary excavation associated with other ocular and/or non-ocular anomalies. Results: In the 1st case the defect concerned both papillae It is associated with other ocular malformations (bilateral macular reshaping and unilateral cataract), without associated cerebral defects. Discussion: The Morning Glory Syndrome is part of the group of congenital defects of the optic nerve. Conclusion: Morning Glory Syndrome through papillary excavation and other associated ocular and/or cerebral malformations may be a threat to vision
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