Morganella morganii bloodstream infection affects the elderly in close contact with health care

Abstract

ObjectivesWe aimed to fill the gaps of knowledge concerning incidence rates and temporal trend, clinical features and risk factors for death for Morganella morganii bloodstream infections (BSIs) in south Sweden. MethodsThis was an observational, population-based study including all patients with at least one blood culture positive for M. morganii between 2013 and 2023 in Skåne, south Sweden. ResultsA total of 211 episodes of M. morganii BSI in 201 patients were registered during the study period. A urinary tract–focused BSI was associated with a reduced risk of 90-day mortality (P = 0.0029), whereas a primary BSI was associated with 90-day mortality (P = 0.0112). A multivariate analysis including age, gender, Charlson comorbidity index (CCI), and immunosuppression revealed that higher CCI (odds ratio [OR] 1.25, 95% confidence interval [CI] 1.07-1.47, P = 0.0059) and immunosuppression (OR 3.26, 95% CI 1.45-7.47, P = 0.0045) was independently associated with all-cause mortality. ConclusionsM. morganii BSI is a disease among the elderly that most often acquired in individuals with comorbidities that are in close contact with health care. A urinary tract focus was associated with reduced risk of 90-day mortality, and higher CCI and immunosuppression were associated with 90-day all-cause mortality in a multivariate analysis.