Abstract

The U.S. Patent and Trademark Office (PTO) has upheld two key patents, on primate and human embryonic stem cells, held by the Wisconsin Alumni Research Foundation, giving WARF a solid victory in its hotly contested patent battle. Last month, PTO upheld a third patent, on stem cell culture techniques (Science, 7 March, p. 1323). The WARF patents, granted in 1995, 1998, and 2001, were challenged 2 years ago by two nonprofits that said the work was obvious and therefore unpatentable. The patent office disagreed, although it narrowed the patents slightly. We applaud this final decision on our two most important base stem cell patents, said the foundation's Carl Gulbrandsen.

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