Abstract

Current WHO guidelines recommend initiation of antiretroviral therapy (ART) in all HIV-infected patients with active tuberculosis (TB), regardless of CD4-cell count, to delay progression of their HIV infection. In this study, investigators examined whether concurrent ART improves response to TB therapy in patients with high CD4-cell counts. They also assessed the significance of having sputum smears positive for acid-fast bacilli (AFB) after 5 months of TB therapy — a situation that, in the absence of sputum …

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