More eyes with 20/10 distance visual acuity at 12 months versus 3 months in a topography-guided excimer laser trial: Possible contributing factors

Abstract

To study eyes with 20/10 uncorrected distance visual acuity (UDVA) 3months and 12months after topography-guided LASIK for myopia and myopic astigmatism, and to identify factors predictive of this excellent level of visual acuity. Nine practices in the USA. Prospective unmasked study of safety and effectiveness. The percentage of eyes with UDVA of 20/10 or better at 3months and 12months after topography-guided laser insitu keratomileusis (LASIK) with the Contoura Vision excimer laser in a U.S. Food and Drug Administration clinical trial was compared, and possible contributing factors were investigated. Preoperatively, only 1% of eyes had 20/10 corrected distance visual acuity (CDVA). Postoperatively, 7.0% of eyes had 20/10 or better UDVA at 3months, and this number increased to 16% at 12months (odds ratio, 2.48; 95% confidence interval, 1.33-4.61). The lower preoperative corneal astigmatism and postoperative refractive cylinder correlated with better postoperative UDVA and CDVA, respectively (P<.01 in all cases). The postoperative UDVA correlated with the postoperative CDVA (P<.01). The number of eyes with UDVA of 20/10 increases significantly between 3months and 12months after topography-guided LASIK and correlates with better postoperative CDVA. Eyes with lower preoperative corneal astigmatism are more likely to achieve 20/10 or better UDVA postoperatively. A significant improvement in the number of eyes with 20/10 or better from 3months to 12months after LASIK might be unique to topography-guided treatment.