Abstract
Inflammatory bowel disease (IBD) is a chronic, sometimes debilitating condition that affects mainly the young population. The effect of IBD on pregnancy is therefore an important clinical issue. Many Obstetricians are likely to come across the occasional patient with this chronic condition. The following article discusses the salient factors which need to be considered in pregnant women with IBD and serves as a quick, practical but nevertheless comprehensive guide for the practicing Obstetrician.
Highlights
Crohn’s disease and Ulcerative colitis are two idiopathic inflammatory bowel disorders that affect young women
Ulcerative colitis is a relapsing non-transmural inflammatory bowel disease that is restricted to the colon
Inflammatory bowel disease is thought to result from an inappropriate and ongoing activation of an aberrant gastrointestinal mucosal immune system driven by normal luminal flora
Summary
Crohn’s disease and Ulcerative colitis are two idiopathic inflammatory bowel disorders that affect young women (and men). The peak age of onset in women is between 15 and 30 years, a period of time during which many women fall pregnant. Significant anxiety is understandably provoked by concerns over heritability to potential offspring, disease flares during pregnancy, adverse pregnancy outcomes and the teratogencity of some therapeutic agents. This article describes both clinical conditions (Crohn’s disease and ulcerative colitis), discusses the way in which they may affect a pregnancy and reviews the literature with regard to recent developments on management in pregnancy. (2015) Morden Management of Inflammatory Bowel Disease in Pregnancy: A Practical Review for Obstetricians.
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