Abstract
As the current COVID-19 pandemic is evolving, skin lesions are being reported more, the most common skin manifestation being morbilliform rashes. We describe a patient of severe COVID-19 infection, 48-year-old who initially presented with fever, cough and constitutional symptoms who developed morbilliform macular rashes during his illness. The rash appeared on 6th day of illness in the trunk, arms with sparing of palms and soles, associated with itching. He later developed features of the cytokine-storm syndrome. The exact mechanism for the rashes is yet to be elaborated, however, it is postulated that it is either due to immune-mediated vasodilation or micro thrombosis secondary to low-grade-coagulopathy associated with COVID-19. Recognition of rashes as a feature of this disease is particularly significant to clinicians as it aids in early diagnosis, particularly in resource-poor countries. There is no evident association, however, between the severity and the rashes in COVID-19 infection.
Highlights
An epidemic of unexplained respiratory infections was reported in Wuhan, China in December 2019; similar to viral pneumonia.1 A new coronavirus was identified after analyses of respiratory samples of patients, and named SARS-CoV-2; the disease was later named Coronavirus disease 2019 (COVID-19).1 As the pandemic evolved, various types of skin lesions were described.2 Skin lesions are fairly common than was generally understood
We describe a patient of COVID-19 infection with generalized morbilliform rashes who subsequently developed the cytokine-storm syndrome
We describe a case of a 48-year-old with COVID infection with fever and cough who subsequently developed features of the cytokine storm
Summary
An epidemic of unexplained respiratory infections was reported in Wuhan, China in December 2019; similar to viral pneumonia.1 A new coronavirus was identified after analyses of respiratory samples of patients, and named SARS-CoV-2; the disease was later named Coronavirus disease 2019 (COVID-19).1 As the pandemic evolved, various types of skin lesions were described.2 Skin lesions are fairly common than was generally understood. Recalcati et al, reported 20.4% of COVID-19 patients developed skin manifestations.3 The most common skin lesion was morbilliform maculopapular rashes, present in 36.1% of patients.4 We describe a patient of COVID-19 infection with generalized morbilliform rashes who subsequently developed the cytokine-storm syndrome. On 6th day of illness, he developed papular-to-plaque rashes over his arms and legs, which progressed to the abdomen and later generalized all over his body.
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